2oph: Difference between revisions

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m Protected "2oph" [edit=sysop:move=sysop]
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[[Category: Scapin, G.]]
[[Category: Scapin, G.]]
[[Category: Weber, A E.]]
[[Category: Weber, A E.]]
[[Category: Alpha/beta]]
[[Category: Beta-propeller]]
[[Category: Dimer]]
[[Category: Hydrolase]]
[[Category: Selective inhibitor]]
[[Category: Type 2 diabetes]]

Revision as of 07:17, 16 March 2011

File:2oph.png

Template:STRUCTURE 2oph

Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor

Template:ABSTRACT PUBMED 17350841

About this Structure

2oph is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE. 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorg Med Chem Lett. 2007 May 15;17(10):2879-85. Epub 2007 Feb 25. PMID:17350841 doi:10.1016/j.bmcl.2007.02.066

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