Lipase: Difference between revisions
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[[1hlg]] – hLip – human - gastric<br /> | [[1hlg]] – hLip – human - gastric<br /> | ||
[[3jw8]], [[3hju]] – mono-glyceride hLip<br /> | [[3jw8]], [[3hju]] – mono-glyceride hLip<br /> | ||
[[1jmy]] – | [[1jmy]] – hBSSL <br /> | ||
[[1akn]] – | [[1akn]] – cBSSL – cattle <br /> | ||
[[ | [[2bce]] - cBSSL (mutant) <br /> | ||
[[1f6w]] - cBSSL – catalytic domain<br /> | |||
[[ | |||
[[3o0d]] – Lip – ''Yarrowia lipolytica'' | [[3o0d]] – Lip – ''Yarrowia lipolytica'' | ||
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[[1eth]], [[1lpa]] - Lip+colipase II - pig<br /> | [[1eth]], [[1lpa]] - Lip+colipase II - pig<br /> | ||
===Hormone-sensitive-lipases ( | ===Hormone-sensitive-lipases (LIPE) hydrolyze the first fatty acid of the triacylglycerol substrate=== | ||
[[3k6k]] – EstE7( | [[3k6k]] – EstE7(LIPE) – metagenome library<br /> | ||
[[3fak]], [[3dnm]] – EstE5( | [[3fak]], [[3dnm]] – EstE5(LIPE) – metagenome library<br /> | ||
[[1evq]] – AaEst2( | [[1evq]] – AaEst2(LIPE) – ''Alicyclobacillus acidocaldarius''<br /> | ||
[[1u4n]] – AaEst2( | [[1u4n]] – AaEst2(LIPE) (mutant) <br /> | ||
===Putative lipases; Proteins with unknown function but structural similarity to lipase obtained in structural genomics projects. === | ===Putative lipases; Proteins with unknown function but structural similarity to lipase obtained in structural genomics projects. === | ||
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[[2pbl]] – Lip - ''Silicibacter'' | [[2pbl]] – Lip - ''Silicibacter'' | ||
===Lipase inhibitors=== | ===Lipase + inhibitors=== | ||
[[3jwe]] - mono-glyceride hLip + SAR629 – covalent inhibitor<br /> | [[3jwe]], [[3pe6]] - mono-glyceride hLip + SAR629 – covalent inhibitor<br /> | ||
[[3l1h]] – EstE5( | [[3l1h]] – EstE5(LIPE)+FeCl3 – noninvasive inhibitor<br /> | ||
[[3l1i]], [[3l1j]] - EstE5( | [[3l1i]], [[3l1j]] - EstE5(LIPE)+CuSO4 – noninvasive inhibitor<br /> | ||
[[3lij]] - EstE5( | [[3lij]] - EstE5(LIPE)+ZnSO4– noninvasive inhibitor<br /> | ||
[[3h18]], [[3h17]] - EstE5 ( | [[3h18]], [[3h17]] - EstE5 (LIPE)+PMSF <br /> | ||
[[3h19]], [[3h1b]], [[3h1a]] – EstE5 ( | [[3h19]], [[3h1b]], [[3h1a]] – EstE5 (LIPE)+methyl alcohol<br /> | ||
[[3h1a]] – EstE5 | [[3h1a]] – EstE5 SLIPE)+ethyl alcohol<br /> | ||
[[3h19]] – EstE5 | [[3h19]] – EstE5 SLIPE)+isopropyl alcohol<br /> | ||
[[3g9t]], [[3g9u]] - EstE5 ( | [[3g9t]], [[3g9u]] - EstE5 (HSLIPE)+p-nitrophenyl butyrate<br /> | ||
[[3g9z]] - EstE5 ( | [[3g9z]] - EstE5 (LIPE) +p-nitrophenyl caprylate<br /> | ||
[[2nw6]] – BcLip+ S inhibitor <br /> | [[2nw6]] – BcLip+ S inhibitor <br /> | ||
[[4lip]], [[5lip]], [[1r4z]], [[1r50]] – BcLip+ Rc-(Rp,Sp)-1,2-dioctylcarbamoyl-glycero-3-O-phosphonate<br /> | [[4lip]], [[5lip]], [[1r4z]], [[1r50]] – BcLip+ Rc-(Rp,Sp)-1,2-dioctylcarbamoyl-glycero-3-O-phosphonate<br /> | ||
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[[1lpn]] – CrLip+ dodecanesulfonate <br /> | [[1lpn]] – CrLip+ dodecanesulfonate <br /> | ||
[[1lpo]], [[1lpp]] – CrLip+ hexadecanesulfonate <br /> | [[1lpo]], [[1lpp]] – CrLip+ hexadecanesulfonate <br /> | ||
[[1qz3]] – | [[1qz3]] – EaEst2(mutant) (LIPE)+hexadecanesulfonate <br /> | ||
===Lipase showing bile-salt binding site=== | ===Lipase showing bile-salt binding site=== | ||
[[1aql]] – | [[1aql]] – cBSSL+taurocholate <br /> | ||
===Lipase with substrate bound at active site=== | ===Lipase with substrate bound at active site=== | ||