Sandbox Reserved 162: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
__TOC__ | __TOC__ | ||
== Background == | == Background == | ||
Human Interleukin-6 (IL-6) is a immune protein often categorized under hematopoietins. Since its discoverey, it has been known by many names including: interferon-ß2 (IFN-ß2), 26-kD protein, B-cell stimulatory factor-2 (BSF-2), hepatocyte stimulating factor (HSF), cytotoxic T-cell differentiation factor (CDF), interleukin-HP1 (IL-HP1), monocyte-granulocyte inducer type 2 (MGI-2), and hybridoma/plasmacytoma growth factor (HPGF/HGF). It wasn't until December of 1988 that is was givin the final moniker of IL-6 (PDB: 1IL6). The protein encoded by this gene is a subunit of the receptor complex for IL6. | Human Interleukin-6 (IL-6) is a immune protein often categorized under [[hematopoietins]]. Since its discoverey, it has been known by many names including: interferon-ß2 (IFN-ß2), 26-kD protein, B-cell stimulatory factor-2 (BSF-2), hepatocyte stimulating factor (HSF), cytotoxic T-cell differentiation factor (CDF), interleukin-HP1 (IL-HP1), monocyte-granulocyte inducer type 2 (MGI-2), and hybridoma/plasmacytoma growth factor (HPGF/HGF). It wasn't until December of 1988 that is was givin the final moniker of IL-6 (PDB: 1IL6). The protein encoded by this gene is a subunit of the receptor complex for IL6. | ||
== Structure == | == Structure == | ||
| Line 9: | Line 9: | ||
== Functions == | == Functions == | ||
Interleukin 6 (IL6) is a potent polyfunctional cytokine that plays a vital role in host defense. This is demonstrated by its potent ability to induce acute-phase responses in the liver. | Interleukin 6 (IL6) is a potent polyfunctional [[cytokine]] that plays a vital role in host defense. This is demonstrated by its potent ability to induce acute-phase responses in the liver. | ||
== IL-6 Receptor == | == IL-6 Receptor == | ||
