Sandbox Reserved 196: Difference between revisions
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== Introduction == | == Introduction == | ||
RNase B is a glycoprotein that can that cleave N-linked carbohydrates. RNase B is structurally the same as RNase A. However is has an additional catalytic activity caused by the attachment of polysaccharrides at the Asn-34. This small change allows RNase B to hydrolyze double-stranded RNA at ionic strengths where RNase A has no activity. This shows that small changes in the active sites of very similar molecules can lead to todally new roles and activities. | RNase B is a glycoprotein that can that cleave N-linked carbohydrates <ref>New England Bio Lab, INC http://www.neb.com/nebecomm/products/productP7817.asp</ref>. RNase B is structurally the same as RNase A. However is has an additional catalytic activity caused by the attachment of polysaccharrides at the Asn-34. This small change allows RNase B to hydrolyze double-stranded RNA at ionic strengths where RNase A has no activity. This shows that small changes in the active sites of very similar molecules can lead to todally new roles and activities <ref>PMID:3680242</ref>. | ||
== Background == | == Background == | ||
[[Image:RNaseB.png | thumb|left|RNase B]] | [[Image:RNaseB.png | thumb|left|RNase B]] | ||
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== References == | == References == | ||
<references /> | |||
== Additional Resources == | == Additional Resources == | ||
<ref group="xtra">Dr. Johnson</ref> | <ref group="xtra">Dr. Johnson</ref> | ||
<references group="xtra"/> | <references group="xtra"/> | ||
