Sandbox Reserved 168: Difference between revisions
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== Background == | == Background == | ||
A proto-oncoprotein is a gene that can become an oncogene, or a gene that has the potential to cause cancer if mutated or if expressed in quantitative amounts. The SKI protein acts as said protooncogene. The SKI protein has been associated with tumors at large levels of cellular concentrations and it has been shown to interfere with normal cellular functioning. | A proto-oncoprotein is a gene that can become an oncogene, or a gene that has the potential to cause cancer if mutated or if expressed in quantitative amounts. The SKI protein acts as said protooncogene. Although The SKI protein has been associated with tumors at large levels of cellular concentrations and it has been shown to interfere with normal cellular functioning. | ||
<ref name="SKI protein"> Reed JA, Lin Q, Chen D, Mian IS, Medrano EE. SKI Pathways Inducing Progression of Human Melanoma. June 2005. http://www.ncbi.nlm.nih.gov/pubmed/15986136</ref>. | <ref name="SKI protein"> Reed JA, Lin Q, Chen D, Mian IS, Medrano EE. SKI Pathways Inducing Progression of Human Melanoma. June 2005. http://www.ncbi.nlm.nih.gov/pubmed/15986136</ref>. | ||
