2xnn: Difference between revisions

Revision as of 08:09, 30 March 2011

2xnn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726

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-'''Unreleased structure'''
+[[Image:2xnn.jpg|left|200px]]
-The entry 2xnn is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_2xnn", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_2xnn|  PDB=2xnn  |  SCENE=  }}
-Authors: Mas-Droux, C., Bayliss, R.
+===STRUCTURE OF NEK2 BOUND TO CCT242430===
-Description: Structure of Nek2 bound to CCT242430
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 23:29:47 2010''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_21366329}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 21366329 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_21366329}}
+==About this Structure==
+[[2xnn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNN OCA].
+==Reference==
+<ref group="xtra">PMID:21366329</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Bayliss, R.]]
+[[Category: Mas-Droux, C.]]