Sandbox Reserved 346: Difference between revisions

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This reaction is essential to maintaining homeostasis in organisms. The four different molecules that can form as a result of this transanimation (oxaloacetate, alpha-ketoglutarate, aspartate, L-glutamate) our critical to a number of metabolic processes. Oxaloacetate and alpha-ketoglutarate play a critical role in the Krebs cycle and the varying forms of aspartate are important molecules in the urea cycle and participates in gluconeogenesis.

=='''Clinical Applications'''==

The levels of AST in the body are indicitive of tissue damage and disease. Normally AST is found in minimal amounts within the blood, however when the organs mentioned above are damaged, AST is released into the blood. The amount released is proportional to the level of damage sustained. AST levels have beenn shown to rise substantially within 6 hours of the initial tissue degradation and can stay elevated for up to 4 days.

The levels of AST in the body are indicitive of tissue damage and disease. Normally AST is found in minimal amounts within the blood, however when the organs mentioned above are damaged, AST is released into the blood. The amount released is proportional to the level of damage sustained. AST levels have beenn shown to rise substantially within 6 hours of the initial tissue degradation and can stay elevated for up to 4 days. AST levels when compared with the levels of other enzymes can be used by physicians to determine where in the body the damge has taken place. Comparisons with ALT have proven particularly useful in identifying liver damage such as cirrhosis and hepatitis. Under normal condition, AST levels within men are 6-34 IU/L and for women it is 8 - 40 IU/L.

AST levels when compared with the levels of other enzymes can be used by physicians to determine where in the body the damge has taken place. Comparisons with ALT have proven particularly useful in identifying liver damage such as cirrhosis and hepatitis.

=='''Additional Resources'''==

=='''References'''==

Sandbox Reserved 346: Difference between revisions

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@@ Line 27: / Line 27: @@
 This reaction is essential to maintaining homeostasis in organisms. The four different molecules that can form as a result of this transanimation (oxaloacetate, alpha-ketoglutarate, aspartate, L-glutamate) our critical to a number of metabolic processes.  Oxaloacetate and alpha-ketoglutarate play a critical role in the Krebs cycle and the varying forms of aspartate are important molecules in the urea cycle and participates in gluconeogenesis.
 =='''Clinical Applications'''==
-The levels of AST in the body are indicitive of tissue damage and disease. Normally AST is found in minimal amounts within the blood, however when the organs mentioned above are damaged, AST is released into the blood. The amount released is proportional to the level of damage sustained. AST levels have beenn shown to rise substantially within 6 hours of the initial tissue degradation and can stay elevated for up to 4 days.
+The levels of AST in the body are indicitive of tissue damage and disease. Normally AST is found in minimal amounts within the blood, however when the organs mentioned above are damaged, AST is released into the blood. The amount released is proportional to the level of damage sustained. AST levels have beenn shown to rise substantially within 6 hours of the initial tissue degradation and can stay elevated for up to 4 days. AST levels when compared with the levels of other enzymes can be used by physicians to determine where in the body the damge has taken place. Comparisons with ALT have proven particularly useful in identifying liver damage such as cirrhosis and hepatitis. Under normal condition, AST levels within men are 6-34 IU/L and for women it is 8 - 40 IU/L.
-AST levels when compared with the levels of other enzymes can be used by physicians to determine where in the body the damge has taken place. Comparisons with ALT have proven particularly useful in identifying liver damage such as cirrhosis and hepatitis.
 =='''Additional Resources'''==
 =='''References'''==