Prp19: Difference between revisions
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Studies have found that PRP19 associates with the spliceosome around the time that the U4 snRNP disassociates from the complex. This is thought to be evidence towards PRP19's involvement in the conformational rearrangement that occurs at this stage of the splicing process.<ref name ="functional"/> Other evidence suggests that PRP19 acts to stabilize the association of U5 and U6 with the active spliceosome.<ref name =" | Studies have found that PRP19 associates with the spliceosome around the time that the U4 snRNP disassociates from the complex. This is thought to be evidence towards PRP19's involvement in the conformational rearrangement that occurs at this stage of the splicing process.<ref name ="functional"/> Other evidence suggests that PRP19 acts to stabilize the association of U5 and U6 with the active spliceosome.<ref name ="2004EMBO">PMID:15175653</ref> | ||
==References== | ==References== | ||
<references /> | <references /> | ||
