Prp19: Difference between revisions

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==Structure==
==Structure==
In Humans, the gene which is homologous to that of PRP19 in ''S. cerevisiae'' is located on chromosome 11 (11q12.2).<ref>"Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27339.</ref> The protein is 503 amino acid residues in length and two majors functional domains have been identified, the WD40 domain and the U Box domain<ref>pmid:20462492</ref>
In Humans, the gene which is homologous to that of PRP19 in ''S. cerevisiae'' is located on chromosome 11 (11q12.2).<ref>"Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27339.</ref> The protein is 503 amino acid residues in length and two majors functional domains have been identified, the WD40 domain and the U Box domain<ref>pmid:20462492</ref>
[[Image:2BAY.jpg]]
[[Image:2bay_small.jpg]]


==Role in Splicing==
==Role in Splicing==