Sandbox Reserved 309: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Hezzy Cody (talk | contribs) No edit summary |
Hezzy Cody (talk | contribs) No edit summary |
||
| Line 10: | Line 10: | ||
Protein of 201 residues with a <scene name='Sandbox_Reserved_309/Ligand/1'>Ligand</scene> consisting of two molecules of ADP (Adenosine-5'-Phosphate) and Magnesium ion. <Structure load=2cdn size='200' frame='true' align='right' caption= 'Adenosine-5'-Diphosphate and Mg' scene='Sandbox_Reserved_309/Ligand/1'/> | Protein of 201 residues with a <scene name='Sandbox_Reserved_309/Ligand/1'>Ligand</scene> consisting of two molecules of ADP (Adenosine-5'-Phosphate) and Magnesium ion. <Structure load=2cdn size='200' frame='true' align='right' caption= 'Adenosine-5'-Diphosphate and Mg' scene='Sandbox_Reserved_309/Ligand/1'/> | ||
==The solution structure== | ==The solution structure== | ||
With no ligand, is represented by a central CORE domain composed of a 5-stranded parallel beta sheet surrounded by 7 alpha helices, and two periferal domains, LID and NMP, these two binding regions participate in the isolation of the substrates during catalysis and usually undergo significant conformational changes during the reaction <ref name= | With no ligand, is represented by a central CORE domain composed of a 5-stranded parallel beta sheet surrounded by 7 alpha helices, and two periferal domains, LID and NMP <ref name=Miron>PMID:14705932 </ref>, these two binding regions participate in the isolation of the substrates during catalysis and usually undergo significant conformational changes during the reaction <ref name=Bellinzoni>PMID: 16672241 </ref> | ||
==The crystalline structure== | ==The crystalline structure== | ||
Globular with a central core made by a <scene name='Sandbox_Reserved_309/Beta_parallel_sheet/1'>beta parallel sheet</scene> surrounded by alpha helices, a P-loop motif at the N-terminus that binds ATP, and two regions (LID and NMP). <ref name=Bellinzoni>PMID: 16672241 </ref> | Globular with a central core made by a <scene name='Sandbox_Reserved_309/Beta_parallel_sheet/1'>beta parallel sheet</scene> surrounded by alpha helices, a P-loop motif at the N-terminus that binds ATP, and two regions (LID and NMP). <ref name=Bellinzoni>PMID: 16672241 </ref> | ||
