Sandbox Reserved 350: Difference between revisions
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*'''Light A3-C1-C2 Chain''' | *'''Light A3-C1-C2 Chain''' | ||
FVa consists of a conserved '''<font color='red'> β-Barrel framework </font> ''' acting as a scaffold for <font color=' | FVa consists of a conserved '''<font color='red'> β-Barrel framework </font> ''' acting as a scaffold for <font color='orangered'> three loops </font> of the '''C2 domain''' (FVa-C2).<ref name="Pubmed"/> | ||
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'''The FVa-C2''', which is classified as a ''' <font color='red'> distorted jelly-roll </font> β-barrel motif''', which is compossed of '''eight major antiparallel strands''' arranged into two ''' <font color='green'> β-sheets of five </font> and <font color='olive'> three strands </font> ''' packed against one another. | '''The FVa-C2''', which is classified as a ''' <font color='red'> distorted jelly-roll </font> β-barrel motif''', which is compossed of '''eight major antiparallel strands''' arranged into two ''' <font color='green'> β-sheets of five </font> and <font color='olive'> three strands </font> ''' packed against one another. | ||
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Salt bridges located within the "upper" segment ''' <font color=' | Salt bridges located within the "upper" segment ''' <font color='goldenrod'> (Asp61-Arg134) </font>'''--Fig2.--''' and the "lower" segment considered basic, due to the XXX '''basic residues''' present in number and alkalinity?. Both together.. | ||
The C2-Domain of Human coagulation factor is homologous to a larger family of adhesion proteins; Discoidin,but not related to synaptotagmin-like C2 domains.<ref name="Pubmed"/> | The C2-Domain of Human coagulation factor is homologous to a larger family of adhesion proteins; Discoidin,but not related to synaptotagmin-like C2 domains.<ref name="Pubmed"/> | ||
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