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==Chorismate Mutase and Tuberculosis==

Tuberculosis has developed various mechanisms to survive in hostile environments < ref name="CMArt2" />. The emergence of multi-drug resistant tuberculosis and other diseases such as AIDS compound the problem of how to treat tuberculosis < ref name="CMArt2" />. Chorismate mutase may be involved in pathogenesis <ref name="pizza" />. Researchers are currently looking into new antimicrobial drugs for diseases such as tuberculosis <ref name="pizza" />. These new drugs would take advantage of the fact that chorismate mutase and the shikimate pathway do not occur in humans, to target and treat various forms of tuberculosis < ref name="pizza" />. ''M. tuberculosis'' chorismate mustase is believed to have a role in the survival of ''M. tuberculosis'' < ref name="CMArt2" />. Two genes in ''M. tuberculosis'', Rv0948c and Rv1885c code for chorismate mutase < ref name="CMArt2" />. These help support ''M. tuberculosis'' when aromatic amino acids, such as tryptophan, tyrosine, and phenylalanine, are deficient < ref name="CMArt2" />. Some researchers have proposed that a proline-rich section of ''M. tuberculosis'' chorismate mutase might be responsible for it binding to the surface receptors on the host cell marcophages <ref name="CMW1"> PMID: 16752890. </ref>.

Tuberculosis has developed various mechanisms to survive in hostile environments <ref name="CMArt2" />. The emergence of multi-drug resistant tuberculosis and other diseases such as AIDS compound the problem of how to treat tuberculosis <ref name="CMArt2" />. Chorismate mutase may be involved in pathogenesis <ref name="pizza" />. Researchers are currently looking into new antimicrobial drugs for diseases such as tuberculosis <ref name="pizza" />. These new drugs would take advantage of the fact that chorismate mutase and the shikimate pathway do not occur in humans, to target and treat various forms of tuberculosis <ref name="pizza" />. ''M. tuberculosis'' chorismate mustase is believed to have a role in the survival of ''M. tuberculosis'' <ref name="CMArt2" />. Two genes in ''M. tuberculosis'', Rv0948c and Rv1885c code for chorismate mutase <ref name="CMArt2" />. These help support ''M. tuberculosis'' when aromatic amino acids, such as tryptophan, tyrosine, and phenylalanine, are deficient <ref name="CMArt2" />. Some researchers have proposed that a proline-rich section of ''M. tuberculosis'' chorismate mutase might be responsible for it binding to the surface receptors on the host cell marcophages <ref name="CMW1"> PMID: 16752890. </ref>.

==References==

Sandbox Reserved 325: Difference between revisions

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 ==Chorismate Mutase and Tuberculosis==
-Tuberculosis has developed various mechanisms to survive in hostile environments < ref name="CMArt2" />.  The emergence of multi-drug resistant tuberculosis and other diseases such as AIDS compound the problem of how to treat tuberculosis < ref name="CMArt2" />.  Chorismate mutase may be involved in pathogenesis <ref name="pizza" />.  Researchers are currently looking into new antimicrobial drugs for diseases such as tuberculosis <ref name="pizza" />.  These new drugs would take advantage of the fact that chorismate mutase and the shikimate pathway do not occur in humans, to target and treat various forms of tuberculosis < ref name="pizza" />.  ''M. tuberculosis'' chorismate mustase is believed to have a role in the survival of ''M. tuberculosis'' < ref name="CMArt2" />.  Two genes in ''M. tuberculosis'', Rv0948c and Rv1885c code for chorismate mutase < ref name="CMArt2" />. These help support ''M. tuberculosis'' when aromatic amino acids, such as tryptophan, tyrosine, and phenylalanine, are deficient < ref name="CMArt2" />.  Some researchers have proposed that a proline-rich section of ''M. tuberculosis'' chorismate mutase might be responsible for it binding to the surface receptors on the host cell marcophages <ref name="CMW1"> PMID: 16752890. </ref>.
+Tuberculosis has developed various mechanisms to survive in hostile environments <ref name="CMArt2" />.  The emergence of multi-drug resistant tuberculosis and other diseases such as AIDS compound the problem of how to treat tuberculosis <ref name="CMArt2" />.  Chorismate mutase may be involved in pathogenesis <ref name="pizza" />.  Researchers are currently looking into new antimicrobial drugs for diseases such as tuberculosis <ref name="pizza" />.  These new drugs would take advantage of the fact that chorismate mutase and the shikimate pathway do not occur in humans, to target and treat various forms of tuberculosis <ref name="pizza" />.  ''M. tuberculosis'' chorismate mustase is believed to have a role in the survival of ''M. tuberculosis'' <ref name="CMArt2" />.  Two genes in ''M. tuberculosis'', Rv0948c and Rv1885c code for chorismate mutase <ref name="CMArt2" />. These help support ''M. tuberculosis'' when aromatic amino acids, such as tryptophan, tyrosine, and phenylalanine, are deficient <ref name="CMArt2" />.  Some researchers have proposed that a proline-rich section of ''M. tuberculosis'' chorismate mutase might be responsible for it binding to the surface receptors on the host cell marcophages <ref name="CMW1"> PMID: 16752890. </ref>.
 ==References==
 <references/>