Sandbox Reserved 301: Difference between revisions
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<ref name="Abad">PMID:12196524</ref> | <ref name="Abad">PMID:12196524</ref> | ||
<ref name="Abad"/> | <ref name="Abad"/> | ||
Escherichia coli Branching Enzyme (BE) (1,4-a-glucan 6-glucosyltransferase)catalyzes the formation of a-1,6 branch points of glycogen <ref name=" | Escherichia coli Branching Enzyme (BE) (1,4-a-glucan 6-glucosyltransferase)catalyzes the formation of a-1,6 branch points of glycogen <ref name="Abad"/>. The enzyme contains three domains: a NH2-terminal seven stranded b-sandwich domain, a COOH-terminal domain, and a central a/b-barrel domain containing the enzyme active site <ref name="Abad"/>. The branching enzyme belongs to the a-amylase family of enzymes<ref name="Abad"/>. | ||
__TOC__ | __TOC__ | ||
=Function= | =Function= | ||
Branching Enzymes contributes to the structure of startch in plants and glycogen in animals and bacteria by catalyzing the formation of a-1,6 brach points in the polysaccharides. The polysaccharide is cleaved at the a-1,4 glucosidic linkage, yidleing a non-reducing end oligosaccharide chain and subsequent attachment to the a-1,6 position. Branching of polysaccharides increased the number of non-reducing ends which makes glycogen more reactive to synthesis and digestion, alos essential for assuring its solubility in the cell (as shown in Figure 1). | Branching Enzymes contributes to the structure of startch in plants and glycogen in animals and bacteria by catalyzing the formation of a-1,6 brach points in the polysaccharides<ref name="Abad"/>. The polysaccharide is cleaved at the a-1,4 glucosidic linkage, yidleing a non-reducing end oligosaccharide chain and subsequent attachment to the a-1,6 position<ref name="Abad"/>. Branching of polysaccharides increased the number of non-reducing ends which makes glycogen more reactive to synthesis and digestion, alos essential for assuring its solubility in the cell (as shown in Figure 1)<ref name="Abad"/>. | ||
=Glyogen Storage Disease type IV= | =Glyogen Storage Disease type IV= | ||
