Cassady sandbox1: Difference between revisions

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==Role in Glycolysis==

Glycolysis is the process of breaking down glucose to make pyruvic acid, which is used in anaerobic respiration or as one of the starting reactants in the citric acid cycle. The process releases some energy but more importantly paves the way for vast amounts of energy to be made through the citric acid cycle. After glucose has been phosphorylated and isomerized to Fructose-6-phospate, PFK begins its work. It phosphorylates the hydroxy group at the number one carbon, which was impossible in glucose. This second phosphorylation by PFK is important because it makes a doubly-high-energy compound. High energy compounds, like Fructose-6-phosphate and Fructose-1,6-bisphosphate, help to drive the endergonic processes of glycolysis through their own exergonic breakdown.<ref>Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. Hoboken, NJ: Wiley, 2008. Print.</ref>. It is important then that PFK makes a bisphosphate compound, ~~beacause~~ eventually that molecule will be cut in half. Thus, after the action of PFK, the six-carbon compound can be broken into two high-energy three-carbon compounds, which are both ready to move onto the next steps of glycolysis.

Glycolysis is the process of breaking down glucose to make pyruvic acid, which is used in anaerobic respiration or as one of the starting reactants in the citric acid cycle. The process releases some energy but more importantly paves the way for vast amounts of energy to be made through the citric acid cycle. After glucose has been phosphorylated and isomerized to Fructose-6-phospate, PFK begins its work. It phosphorylates the hydroxy group at the number one carbon, which was impossible in glucose. This second phosphorylation by PFK is important because it makes a doubly-high-energy compound. High energy compounds, like Fructose-6-phosphate and Fructose-1,6-bisphosphate, help to drive the endergonic processes of glycolysis through their own exergonic breakdown.<ref>Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. Hoboken, NJ: Wiley, 2008. Print.</ref>. It is important then that PFK makes a bisphosphate compound, because eventually that molecule will be cut in half. Thus, after the action of PFK, the six-carbon compound can be broken into two high-energy three-carbon compounds, which are both ready to move onto the next steps of glycolysis.

==Structure==

Cassady sandbox1: Difference between revisions

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 ==Role in Glycolysis==
-Glycolysis is the process of breaking down glucose to make pyruvic acid, which is used in anaerobic respiration or as one of the starting reactants in the citric acid cycle. The process releases some energy but more importantly paves the way for vast amounts of energy to be made through the citric acid cycle. After glucose has been phosphorylated and isomerized to Fructose-6-phospate, PFK begins its work. It phosphorylates the hydroxy group at the number one carbon, which was impossible in glucose. This second phosphorylation by PFK is important because it makes a doubly-high-energy compound. High energy compounds, like Fructose-6-phosphate and Fructose-1,6-bisphosphate, help to drive the endergonic processes of glycolysis through their own exergonic breakdown.<ref>Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. Hoboken, NJ: Wiley, 2008. Print.</ref>. It is important then that PFK makes a bisphosphate compound, beacause eventually that molecule will be cut in half. Thus, after the action of PFK, the six-carbon compound can be broken into two high-energy three-carbon compounds, which are both ready to move onto the next steps of glycolysis.
+Glycolysis is the process of breaking down glucose to make pyruvic acid, which is used in anaerobic respiration or as one of the starting reactants in the citric acid cycle. The process releases some energy but more importantly paves the way for vast amounts of energy to be made through the citric acid cycle. After glucose has been phosphorylated and isomerized to Fructose-6-phospate, PFK begins its work. It phosphorylates the hydroxy group at the number one carbon, which was impossible in glucose. This second phosphorylation by PFK is important because it makes a doubly-high-energy compound. High energy compounds, like Fructose-6-phosphate and Fructose-1,6-bisphosphate, help to drive the endergonic processes of glycolysis through their own exergonic breakdown.<ref>Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. Hoboken, NJ: Wiley, 2008. Print.</ref>. It is important then that PFK makes a bisphosphate compound, because eventually that molecule will be cut in half. Thus, after the action of PFK, the six-carbon compound can be broken into two high-energy three-carbon compounds, which are both ready to move onto the next steps of glycolysis.
 ==Structure==