Sandbox Reserved 194: Difference between revisions

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Further binding pocket characterization was accomplished using the oglionucleotide <scene name='Sandbox_Reserved_194/1rcn_just_dtda/1'>d(ApTpApApG)</scene>.   
Further binding pocket characterization was accomplished using the oglionucleotide <scene name='Sandbox_Reserved_194/1rcn_just_dtda/1'>d(ApTpApApG)</scene>.   
While binding of other nucleobases to the B2 and B3 sites is possible, the imaging of this <scene name='Sandbox_Reserved_194/1rcn_structure/2'>complex </scene>elucidated the  preferences  
While binding of other nucleobases to the B2 and B3 sites is possible, the imaging of this <scene name='Sandbox_Reserved_194/1rcn_structure/2'>complex </scene>elucidated the  preferences  
for adenosine bases at these two positions.  RNase A establishes <scene name='Sandbox_Reserved_194/1rcn_his/8'>pi stacking between His119 and A3 </scene>in addition to hydrogen bonding between <scene name='Sandbox_Reserved_194/1rcn_hydrogen_bonding/7'>Asn71-A3, Gln69-A3 and Gln69-A4</scene>. ‘<ref>PMID:8063789</ref>’     
for adenosine bases at these two positions.  RNase A establishes <scene name='Sandbox_Reserved_194/1rcn_his/9'>pi stacking between His119 and A3 </scene>in addition to hydrogen bonding between <scene name='Sandbox_Reserved_194/1rcn_hydrogen_bonding/9'>Asn71-A3, Gln69-A3 and Gln69-A4</scene>. ‘<ref>PMID:8063789</ref>’     




== References ==
== References ==
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