Sandbox Reserved 194: Difference between revisions
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Further binding pocket characterization was accomplished using the oglionucleotide <scene name='Sandbox_Reserved_194/1rcn_just_dtda/1'>d(ApTpApApG)</scene>. | Further binding pocket characterization was accomplished using the oglionucleotide <scene name='Sandbox_Reserved_194/1rcn_just_dtda/1'>d(ApTpApApG)</scene>. | ||
While binding of other nucleobases to the B2 and B3 sites is possible, the imaging of this <scene name='Sandbox_Reserved_194/1rcn_structure/2'>complex </scene>elucidated the preferences | While binding of other nucleobases to the B2 and B3 sites is possible, the imaging of this <scene name='Sandbox_Reserved_194/1rcn_structure/2'>complex </scene>elucidated the preferences | ||
for adenosine bases at these two positions. RNase A establishes <scene name='Sandbox_Reserved_194/1rcn_his/ | for adenosine bases at these two positions. RNase A establishes <scene name='Sandbox_Reserved_194/1rcn_his/9'>pi stacking between His119 and A3 </scene>in addition to hydrogen bonding between <scene name='Sandbox_Reserved_194/1rcn_hydrogen_bonding/9'>Asn71-A3, Gln69-A3 and Gln69-A4</scene>. ‘<ref>PMID:8063789</ref>’ | ||
== References == | == References == | ||
<references/> | <references/> | ||