Sandbox Reserved 194: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 8: Line 8:
<Structure load='1RTA' size='450' frame='true' align='right' caption='Ribonuclease A complexed with thymidylic acid tetramer and ApTpApApG showing pi stacking and hydrogen bonding ' scene='Sandbox_Reserved_194/1rta_structure/2'/>
<Structure load='1RTA' size='450' frame='true' align='right' caption='Ribonuclease A complexed with thymidylic acid tetramer and ApTpApApG showing pi stacking and hydrogen bonding ' scene='Sandbox_Reserved_194/1rta_structure/2'/>


RNase A is an endonuclease that cleaves and breaks down RNA using acid base catalysis (link to sandbox 193). RNase A has been a model protein for studies on the stability, folding and chemistry of proteins. ‘<ref>PMID:11848924</ref>’ It is also essential in protein regulation within the body due to its function of RNA degradation.  
RNase A is an endonuclease that cleaves and breaks down RNA using acid base catalysis. RNase A has been a model protein for studies on the stability, folding and chemistry of proteins. ‘<ref>PMID:11848924</ref>’ It is also essential in protein regulation within the body due to its function of RNA degradation.  


== Substrate Binding ==
== Substrate Binding ==
Line 27: Line 27:
== References ==
== References ==
<references/>
<references/>
== External Resources ==
* [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RTA Full crystal structure of 1RTA]
* [http://oca.weizmann.ac.il/oca-bin/ocashort Full crystal structure of 1RCN]
* [http://www.proteopedia.org/wiki/index.php/1rta Further information on 1RTA]
* [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb105_1.html RNase A- Molecule of the Month]