Sandbox Reserved 403: Difference between revisions

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<Structure load='1fv2' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />


==Tetanospasmin(Tetanus Neurotoxin(TeNT)==<StructureSection load='1fv2' size='500' side='right' caption='Structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue (PDB entry 1fv2)' scene=''><scene name='Sandbox_Reserved_403/Secondary_structure/1'>Secondary Structure</scene>


<scene name='Sandbox_Reserved_403/Secondary_structure/2'>The Gal-GalNAc-binding site</scene>
<scene name='Sandbox_Reserved_403/Sia7-sia6-binding_site/2'>The Sia7-Sia6 binding site</scene>


==Tetanospasmin(Tetanus Neurotoxin(TeNT)==<StructureSection load='1fv2' size='500' side='right' caption='Structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue (PDB entry 1fv2)' scene=''><scene name='Sandbox_Reserved_403/Secondary_structure/1'>TextToBeDisplayed</scene><scene name='Sandbox_Reserved_403/Secondary_structure/2'>The Gal-GalNAc-binding site</scene><scene name='Sandbox_Reserved_403/Sia7-sia6-binding_site/2'>The Sia7-Sia6 binding site</scene><scene name='Sandbox_Reserved_403/Binding_site_2/1'>Both Binding sites</scene></StructureSection>
<scene name='Sandbox_Reserved_403/Binding_site_2/1'>Both Binding sites</scene></StructureSection>


== Clostidium tetani ==
== Clostidium tetani ==
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Commonly hydrogen bonds form between OD-1 and OD-2 of Asp1147 and O-4 and the acetamido-N-5 of Sia6 and between ND-2 of Asn1216 and O-10 of Sia6. A salt bridge also forms between Arg1226 and the sialic acid of Sia7, also the carboxylate group and hydrogen bonds between O-1A and the amide NH of Asn1216; between O-4 and the carbonyl oxygen of Asp1214; and betweenOH-8 and Tyr1229 hydroxyl group on Sia7.<ref>PMID: 11418600 </ref>
Commonly hydrogen bonds form between OD-1 and OD-2 of Asp1147 and O-4 and the acetamido-N-5 of Sia6 and between ND-2 of Asn1216 and O-10 of Sia6. A salt bridge also forms between Arg1226 and the sialic acid of Sia7, also the carboxylate group and hydrogen bonds between O-1A and the amide NH of Asn1216; between O-4 and the carbonyl oxygen of Asp1214; and betweenOH-8 and Tyr1229 hydroxyl group on Sia7.<ref>PMID: 11418600 </ref>


<scene name='Sandbox_Reserved_403/Binding_site/1'>TextToBeDisplayed</scene>




<scene name='Sandbox_Reserved_403/Secondary_structure/1'>TextToBeDisplayed</scene>
<scene name='Sandbox_Reserved_403/Secondary_structure/2'>The Gal-GalNAc-binding site</scene>
<scene name='Sandbox_Reserved_403/Sia7-sia6-binding_site/2'>The Sia7-Sia6 binding site</scene>
<scene name='Sandbox_Reserved_403/Binding_site/1'>TextToBeDisplayed</scene>
<scene name='Sandbox_Reserved_403/Binding_site_2/1'>Both Binding sites</scene>




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