2x6d: Difference between revisions

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Revision as of 09:46, 21 April 2011

File:2x6d.png

Template:STRUCTURE 2x6d

AURORA-A BOUND TO AN INHIBITOR

Template:ABSTRACT PUBMED 20565112

About this Structure

2x6d is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bavetsias V, Large JM, Sun C, Bouloc N, Kosmopoulou M, Matteucci M, Wilsher NE, Martins V, Reynisson J, Atrash B, Faisal A, Urban F, Valenti M, de Haven Brandon A, Box G, Raynaud FI, Workman P, Eccles SA, Bayliss R, Blagg J, Linardopoulos S, McDonald E. Imidazo[4,5-b]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical Development Candidate. J Med Chem. 2010 Jun 21. PMID:20565112 doi:10.1021/jm100262j

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