TonB: Difference between revisions
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==Structure== | ==Structure== | ||
The structure to the right ( | The structure to the right (1XX3) shows the structure of TonB. The protein spans the periplasm <ref>PMID: 16741125</ref>, with the C-terminus of TonB spanning from residues ~150 to 239<ref name='Postle'>PMID: 21179522</ref>. | ||
==Function== | ==Function== | ||
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===BtuB-TonB Complex=== | ===BtuB-TonB Complex=== | ||
TonB complexes with [[BtuB]] in order to aid the transport of nutrients such as cobalamins<ref name='Cadieux'>PMID 11029413</ref> across the outer membrane by incorporating the proton-motive force into the outer membrane.<ref name='Shultis'>PMID: 16741124</ref> TonB attaches to BtuB on the periplasmic side of the 614 amino acid BtuB protein<ref name='Shultis'> PMID: 16741124</ref>. | As shown in the 3D structure to the right (2GSK), TonB complexes with [[BtuB]] in order to aid the transport of nutrients such as cobalamins<ref name='Cadieux'>PMID 11029413</ref> across the outer membrane by incorporating the proton-motive force into the outer membrane.<ref name='Shultis'>PMID: 16741124</ref> TonB attaches to BtuB on the periplasmic side of the 614 amino acid BtuB protein<ref name='Shultis'> PMID: 16741124</ref>. | ||
{{STRUCTURE_2gsk | PDB=2gsk | SCENE= BtuB-TonB_Complex/Btubtonbcomplex/1 }} | {{STRUCTURE_2gsk | PDB=2gsk | SCENE= BtuB-TonB_Complex/Btubtonbcomplex/1 }} | ||
