ExbD: Difference between revisions
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ExbD has been shown to be approximately 25% identical and 70% similar to the [[TolR]] sequence<ref name='Kampfenkel'>PMID: 1644779</ref>, it can be assumed that these two proteins will have a similar arrangement of their sequences. | ExbD has been shown to be approximately 25% identical and 70% similar to the [[TolR]] sequence<ref name='Kampfenkel'>PMID: 1644779</ref>, it can be assumed that these two proteins will have a similar arrangement of their sequences. | ||
==Function== | ==Function== | ||
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ExbD is present in cells only in a complex with [[ExbB]], where is affects the functioning of the TonB complex both in how it responds to the proton motive force as well as its affinity with either the cytoplasmic or outer membrane. <ref>PMID: 12193634</ref> It has also been shown that TolR can replace the function of an ExbD mutant just as [[TolQ]] can with ExbB, suggesting an evolutionary link between the two complexes. | ExbD is present in cells only in a complex with [[ExbB]], where is affects the functioning of the TonB complex both in how it responds to the proton motive force as well as its affinity with either the cytoplasmic or outer membrane. <ref>PMID: 12193634</ref> It has also been shown that TolR can replace the function of an ExbD mutant just as [[TolQ]] can with ExbB, suggesting an evolutionary link between the two complexes. | ||
{{STRUCTURE_2pfu | PDB=2pfu | SCENE= Periplasmic_Domain_of_ExbD/Periplasmicdomainexbd/1 }} | |||
== References== | == References== | ||
<references/> | <references/> | ||
