Pyruvate dehydrogenase: Difference between revisions

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{{STRUCTURE_1l8a | PDB=1l8a | SCENE= }}Pyruvate dehydrogenase (E1) is one of three main components of the multienzyme complex pyruvate ~~dhttp://www.proteopedia.org/wiki/skins/common/images/button_bold.pngehydrogenase~~. It accompanies dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) in comprising this multienzyme complex. The E. coli enzyme complex has a weight of approximately 4600-kD and a diameter of about 300 angstroms. The core of the particle is made of 24 E2 proteins arranged in a cube, which is surrounded by 24 E1 proteins and 12 E3 proteins. Together, these enzymes are responsible for synthesizing acetyl-CoA from pyruvate just prior to entrance into the citric acid cycle. Therefore, pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid pathway.

{{STRUCTURE_1l8a | PDB=1l8a | SCENE= }}Pyruvate dehydrogenase (E1) is one of three main components of the multienzyme complex pyruvate dehydrogenase. It accompanies dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) in comprising this multienzyme complex. The E. coli enzyme complex has a weight of approximately 4600-kD and a diameter of about 300 angstroms. The core of the particle is made of 24 E2 proteins arranged in a cube, which is surrounded by 24 E1 proteins and 12 E3 proteins. Together, these enzymes are responsible for synthesizing acetyl-CoA from pyruvate just prior to entrance into the citric acid cycle. Therefore, pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid pathway.

==Structure==

Pyruvate dehydrogenase: Difference between revisions

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Revision as of 03:09, 2 May 2011 view source Mike Lu (talk \| contribs) 25 edits New page: {{STRUCTURE_1l8a \| PDB=1l8a \| SCENE= }}Pyruvate dehydrogenase (E1) is one of three main components of the multienzyme complex pyruvate dhttp://www.proteopedia.org/wiki/skins/common/ima...		Revision as of 03:10, 2 May 2011 view source Mike Lu (talk \| contribs) 25 edits No edit summary Newer edit →
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	{{STRUCTURE_1l8a \| PDB=1l8a \| SCENE= }}Pyruvate dehydrogenase (E1) is one of three main components of the multienzyme complex pyruvate ~~dhttp://www.proteopedia.org/wiki/skins/common/images/button_bold.pngehydrogenase~~. It accompanies dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) in comprising this multienzyme complex. The E. coli enzyme complex has a weight of approximately 4600-kD and a diameter of about 300 angstroms. The core of the particle is made of 24 E2 proteins arranged in a cube, which is surrounded by 24 E1 proteins and 12 E3 proteins. Together, these enzymes are responsible for synthesizing acetyl-CoA from pyruvate just prior to entrance into the citric acid cycle. Therefore, pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid pathway.		{{STRUCTURE_1l8a \| PDB=1l8a \| SCENE= }}Pyruvate dehydrogenase (E1) is one of three main components of the multienzyme complex pyruvate dehydrogenase. It accompanies dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) in comprising this multienzyme complex. The E. coli enzyme complex has a weight of approximately 4600-kD and a diameter of about 300 angstroms. The core of the particle is made of 24 E2 proteins arranged in a cube, which is surrounded by 24 E1 proteins and 12 E3 proteins. Together, these enzymes are responsible for synthesizing acetyl-CoA from pyruvate just prior to entrance into the citric acid cycle. Therefore, pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid pathway.

	==Structure==		==Structure==