Sandbox20: Difference between revisions
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During fork fusion, it is proposed that the fork arriving at the permissive face of the replication fork trap displaces the terminator protein and causes the disassembly of the replisome. A combination of helicase, toposiomerase, polymerase and ligase then fill the remaining gaps to make a chromosome dimer with the two full-length chromosomes joined. RecQ, topoisomerase III, single-strand binding protein (SSBP) and DNA polymerase I are said to play a role in this process <REF>PMID:18570879 </REF>. Finally, site-specific recombination takes place at the dif site to produce two identical monomeric chromosomes <ref>PMID:15554958 </ref>. | During fork fusion, it is proposed that the fork arriving at the permissive face of the replication fork trap displaces the terminator protein and causes the disassembly of the replisome. A combination of helicase, toposiomerase, polymerase and ligase then fill the remaining gaps to make a chromosome dimer with the two full-length chromosomes joined. RecQ, topoisomerase III, single-strand binding protein (SSBP) and DNA polymerase I are said to play a role in this process <REF>PMID:18570879 </REF>. Finally, site-specific recombination takes place at the dif site to produce two identical monomeric chromosomes <ref>PMID:15554958 </ref>. | ||
=The Proteins= | =The Proteins= | ||
