3r92: Difference between revisions
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[[Image:3r92.jpg|left|200px]] | |||
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{{STRUCTURE_3r92| PDB=3r92 | SCENE= }} | |||
===Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.=== | |||
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{{ABSTRACT_PUBMED_21605975}} | |||
==About this Structure== | |||
[[3r92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R92 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021605975</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Bloom, J D.]] | |||
[[Category: Boschelli, F.]] | |||
[[Category: Dushin, R G.]] | |||
[[Category: Golas, J M.]] | |||
[[Category: Levin, J I.]] | |||
[[Category: Liu, H.]] | |||
[[Category: Lucas, J.]] | |||
[[Category: McBean, J L.]] | |||
[[Category: Vogan, E M.]] | |||
[[Category: Zapf, C W.]] | |||
Revision as of 05:09, 8 June 2011
Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.
Template:ABSTRACT PUBMED 21605975
About this Structure
3r92 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zapf CW, Bloom JD, McBean JL, Dushin RG, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Levin JI. Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3627-31. Epub 2011 Apr 28. PMID:21605975 doi:10.1016/j.bmcl.2011.04.102
