Sandboxjg: Difference between revisions
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Roderick MacKinnon and his team determined the structure of the protein and concluded that it was a channel. In a 2004 article co-authored by Accardi and Miller, it was established that the protein functioned by means of a 2:1 chloride ion-hydrogen ion exchange mechanism. | Roderick MacKinnon and his team determined the structure of the protein and concluded that it was a channel. In a 2004 article co-authored by Accardi and Miller, it was established that the protein functioned by means of a 2:1 chloride ion-hydrogen ion exchange mechanism. | ||
The CLC-ec1 transporter is a protein dimer made up of two functional antiparallel polypeptide chains. The chains extend from the inside to the outside of the plasma membrane creating a passage. Its structure allows it to use electrostatic interactions with alpha-helic dipoles and chemical groups coordinated with nitrogen atoms and carboxyl groups in order to filter Cl- and H+ ions. Because each polypeptide chains functions independently, we will focus on the structure of one pore. | The CLC-ec1 transporter is a protein dimer made up of two functional antiparallel polypeptide chains. The chains extend from the inside to the outside of the plasma membrane creating a passage. Its structure allows it to use electrostatic interactions with alpha-helic dipoles and chemical groups coordinated with nitrogen atoms and carboxyl groups in order to filter Cl- and H+ ions. Because each polypeptide chains functions independently, we will focus on the structure of one pore. | ||
To see the test <scene name='Sandboxjg/Test1ots/1'>click on me</scene> | |||
<scene name='Sandboxjg/1ots/2'>Hi Hi</scene> | |||
