3nu0: Difference between revisions
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[[Image:3nu0. | [[Image:3nu0.png|left|200px]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Cyclized inhibitor]] | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Oxidoreductase hdhfr-264-nadph]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
Revision as of 05:32, 15 June 2011
Design, Synthesis, Biological Evaluation and X-ray Crystal Structure of Novel Classical 6,5,6-TricyclicBenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors
Template:ABSTRACT PUBMED 21550809
About this Structure
3nu0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang X, Zhou X, Kisliuk RL, Piraino J, Cody V, Gangjee A. Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors. Bioorg Med Chem. 2011 Apr 9. PMID:21550809 doi:10.1016/j.bmc.2011.03.067
