3o5n: Difference between revisions
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[[Image:3o5n.jpg|left|200px]] | |||
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{{STRUCTURE_3o5n| PDB=3o5n | SCENE= }} | |||
===Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders=== | |||
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{{ABSTRACT_PUBMED_21626699}} | |||
==About this Structure== | |||
[[3o5n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021626699</ref><references group="xtra"/> | |||
[[Category: Mus musculus]] | |||
[[Category: Diehl, A.]] | |||
[[Category: Heinemann, U.]] | |||
[[Category: Kamdem, N.]] | |||
[[Category: Krause, G.]] | |||
[[Category: Oschkinat, H.]] | |||
[[Category: Rademann, J.]] | |||
[[Category: Radetzki, S.]] | |||
[[Category: Roske, Y.]] | |||
[[Category: Saupe, J.]] | |||
[[Category: Schillinger, C.]] | |||
[[Category: Gkap]] | |||
[[Category: Pdz domain]] | |||
[[Category: Postsynaptic density]] | |||
[[Category: Protein binding]] | |||
[[Category: Protein-protein interaction]] | |||
Revision as of 06:14, 15 June 2011
Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders
Template:ABSTRACT PUBMED 21626699
About this Structure
3o5n is a 8 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Saupe J, Roske Y, Schillinger C, Kamdem N, Radetzki S, Diehl A, Oschkinat H, Krause G, Heinemann U, Rademann J. Discovery, Structure-Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain. ChemMedChem. 2011 May 27. doi: 10.1002/cmdc.201100094. PMID:21626699 doi:10.1002/cmdc.201100094
