Cation-pi interactions: Difference between revisions
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==Examples== | ==Examples== | ||
<table width='370' align='right' cellpadding='5'><tr><td rowspan='2'> </td><td bgcolor='#eeeeee'><applet load='1gai' size='350' frame='true' align='right' scene='Cation-pi_interactions/1gai_pi4/1' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Cation-pi interactions''' </center></td></tr></table> | <table width='370' align='right' cellpadding='5'><tr><td rowspan='2'> </td><td bgcolor='#eeeeee'><applet load='1gai' size='350' frame='true' align='right' scene='Cation-pi_interactions/1gai_pi4/1' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Cation-pi interactions''' </center></td></tr></table> | ||
===Nicotinic Acetylcholine Receptor and Nicotine Addiction=== | |||
The nicotinic acetylcholine receptor is a ligand-gated ion channel that responds to the neurotransmitter acetylcholine. It occurs in the central and peripheral nervous systems, and in the neuromuscular junction that controls muscle contraction. | |||
In 1998, Zhong ''et al.'' (Dougherty Group)<ref name="zhong">PMID: 9770444</ref> provided evidence that the cation in acetylcholine engages in a cation-pi interaction with Trp149 in the | |||
===Examples from Gallivan and Dougherty<ref name='GD' />=== | ===Examples from Gallivan and Dougherty<ref name='GD' />=== | ||
