2wkz: Difference between revisions
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[[Image:2wkz.png|left|200px]] | |||
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==About this Structure== | ==About this Structure== | ||
[[2wkz]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_z2/cdc-z34_group_m_subtype_d) Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WKZ OCA]. | |||
==See Also== | |||
*[[Virus protease]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019961222</ref><references group="xtra"/> | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Axelsson, L.]] | [[Category: Axelsson, L.]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Transition-state mimic]] | [[Category: Transition-state mimic]] | ||
Revision as of 18:04, 6 July 2011
HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY
Template:ABSTRACT PUBMED 19961222
About this Structure
2wkz is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d). Full crystallographic information is available from OCA.
See Also
Reference
- Mahalingam AK, Axelsson L, Ekegren JK, Wannberg J, Kihlstrom J, Unge T, Wallberg H, Samuelsson B, Larhed M, Hallberg A. HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J Med Chem. 2009 Dec 4. PMID:19961222 doi:10.1021/jm901165g