Methotrexate: Difference between revisions
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<Structure load='MTX' size='350' frame='true' align='right' caption='Methotrexate' scene='Insert optional scene name here' /> | <Structure load='MTX' size='350' frame='true' align='right' caption='Methotrexate' scene='Insert optional scene name here' /> | ||
Methotrexate, formerly known as amethopterin, is a drug that is used in the competitive inhibition of [[Dihydrofolate reductase]], resulting in decreased synthesis of dTTP and diminished cellular replication. The antimetabolic nature of methotrexate is most effective against the most rapidly dividing cells, making this drug useful in [[Cancer]] [[Pharmaceutical Drugs|treatment]], and various autoimmune diseases<ref>Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx </ref>. | [[Methotrexate]], formerly known as amethopterin, is a drug that is used in the competitive inhibition of [[Dihydrofolate reductase]], resulting in decreased synthesis of dTTP and diminished cellular replication. The antimetabolic nature of methotrexate is most effective against the most rapidly dividing cells, making this drug useful in [[Cancer]] [[Pharmaceutical Drugs|treatment]], and various autoimmune diseases<ref>Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx </ref>. | ||
==Chemical Properties== | ==Chemical Properties== | ||
