3ras: Difference between revisions

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[[Image:3ras.jpg|left|200px]]
[[Image:3ras.png|left|200px]]


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[[Category: Prasad, B V.V.]]
[[Category: Prasad, B V.V.]]
[[Category: Song, Y.]]
[[Category: Song, Y.]]
[[Category: 1-deoxy-d-xylulose 5-phosphate reductoisomerase]]
[[Category: Doxp/mep pathway]]
[[Category: Isoprene biosynthesis]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-inhibitor complex]]

Revision as of 05:41, 20 July 2011

File:3ras.png

Template:STRUCTURE 3ras

Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor

Template:ABSTRACT PUBMED 21561155

About this Structure

3ras is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR and Crystallographic Studies. J Med Chem. 2011 May 11. PMID:21561155 doi:10.1021/jm200363d

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