3pp7: Difference between revisions
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===Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.=== | ===Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.=== | ||
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==About this Structure== | ==About this Structure== | ||
[[3pp7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP7 OCA]. | [[3pp7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP7 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:021733839</ref><references group="xtra"/> | |||
[[Category: Leishmania mexicana]] | [[Category: Leishmania mexicana]] | ||
[[Category: Pyruvate kinase]] | [[Category: Pyruvate kinase]] | ||
Revision as of 07:47, 3 August 2011
Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.
Template:ABSTRACT PUBMED 21733839
About this Structure
3pp7 is a 2 chain structure with sequence from Leishmania mexicana. Full crystallographic information is available from OCA.
Reference
- Morgan HP, McNae IW, Nowicki MW, Zhong W, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD. The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J Biol Chem. 2011 Jul 5. PMID:21733839 doi:10.1074/jbc.M110.212613
