2uz9: Difference between revisions

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[[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2uz9, resolution 2.30Å" />

'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT ~~XHANTINE~~.'''<br />

'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br />

==Disease==

Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2K OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 4A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]]

==About this Structure==

2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional ~~Site~~: <scene name='pdbsite=AC1:Xan Binding Site For ~~Chain~~ A'>~~AC1~~</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].

2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn Binding Site For Residue A 1452'>AC1</scene> and <scene name='pdbsite=AC2:Xan Binding Site For Residue A 1453'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].

[[Category: Guanine deaminase]]

[[Category: Homo sapiens]]

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[[Category: zinc]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Jan ~~23 15~~:15:31 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 11:00:36 2008''

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@@ Line 1: / Line 1: @@
 [[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2uz9, resolution 2.30&Aring;" />
-'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XHANTINE.'''<br />
+'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br />
+==Disease==
+Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2K OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 4A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]]
 ==About this Structure==
-UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Site: <scene name='pdbsite=AC1:Xan Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].
+UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn Binding Site For Residue A 1452'>AC1</scene> and <scene name='pdbsite=AC2:Xan Binding Site For Residue A 1453'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].
 [[Category: Guanine deaminase]]
 [[Category: Homo sapiens]]
@@ Line 45: / Line 48: @@
 [[Category: zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:15:31 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 11:00:36 2008''