Simvastatin Synthase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
David Canner (talk | contribs) No edit summary |
David Canner (talk | contribs) No edit summary |
||
| Line 4: | Line 4: | ||
LovD can also synthesize the blockbuster drug simvastatin using MJA and a synthetic α-dimethylbutyryl thioester<ref name="paper1">PMID:17277201</ref>. | LovD can also synthesize the blockbuster drug simvastatin using MJA and a synthetic α-dimethylbutyryl thioester<ref name="paper1">PMID:17277201</ref>. | ||
__NOTOC__ | __NOTOC__ | ||
==Exploring the structure== | ==Exploring the structure== | ||
{{STRUCTURE_3hle | PDB=3hle | SCENE= }} | {{STRUCTURE_3hle | PDB=3hle | SCENE= }} | ||
| Line 13: | Line 14: | ||
LovD has <scene name='Sandbox_Reserved_316/Cysteines/2'>nine cysteines</scene> at the following positions: C40, C49, C60, C72, C89, C216, C266, C380, and C395<ref name="paper3">PMID:18988191</ref>. | LovD has <scene name='Sandbox_Reserved_316/Cysteines/2'>nine cysteines</scene> at the following positions: C40, C49, C60, C72, C89, C216, C266, C380, and C395<ref name="paper3">PMID:18988191</ref>. | ||
{clear} | |||
==Additional Information== | ==Additional Information== | ||
<Structure load='1CI8' size='300' frame='true' align='right' caption='' scene='Sandbox_Reserved_316/Estb/1'/> | <Structure load='1CI8' size='300' frame='true' align='right' caption='' scene='Sandbox_Reserved_316/Estb/1'/> | ||
