3s2o: Difference between revisions
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[[Image:3s2o. | [[Image:3s2o.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[3s2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. | [[3s2o]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. | ||
==See Also== | |||
*[[Beta secretase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Madden, J.]] | [[Category: Madden, J.]] | ||
[[Category: Smith, M A.]] | [[Category: Smith, M A.]] | ||
[[Category: Alzheimer's disease]] | |||
[[Category: Amyloid precursor protein secretase]] | |||
[[Category: Aspartic endopeptidase]] | |||
[[Category: Aspartic protease]] | |||
[[Category: Aspartyl protease]] | |||
[[Category: Base]] | |||
[[Category: Beta-secretase]] | |||
[[Category: Fluorescence polarisation]] | |||
[[Category: Fragment-based drug design]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Memapsin 2]] | |||
[[Category: Protease]] | |||
[[Category: Transmembrane]] | |||
Revision as of 05:23, 7 September 2011
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure of Beta secretase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Barker, J.
- Godemann, R.
- Hallett, D.
- Kraemer, J.
- Madden, J.
- Smith, M A.
- Alzheimer's disease
- Amyloid precursor protein secretase
- Aspartic endopeptidase
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Fluorescence polarisation
- Fragment-based drug design
- Glycoprotein
- Hydrolase-hydrolase inhibitor complex
- Protease
- Transmembrane
