3h3b: Difference between revisions

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{{Seed}}
[[Image:3h3b.png|left|200px]]
[[Image:3h3b.jpg|left|200px]]


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==Disease==
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Known disease associated with this structure: Adenocarcinoma of lung, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Gastric cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Glioblastoma, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Ovarian cancer, somatic, OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]]
The line below this paragraph, {{ABSTRACT_PUBMED_21680730}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21680730 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21680730}}


==About this Structure==
==About this Structure==
3H3B is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3B OCA].  
[[3h3b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3B OCA].  
 
==Reference==
<ref group="xtra">PMID:021680730</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Polymorphism]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
[[Category: Receptor]]
[[Category: Receptor]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:03:22 2010''

Revision as of 04:46, 28 September 2011

File:3h3b.png

Template:STRUCTURE 3h3b

Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain

Template:ABSTRACT PUBMED 21680730

About this Structure

3h3b is a 4 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Zhou H, Zha Z, Liu Y, Zhang H, Zhu J, Hu S, Shen G, Cheng L, Niu L, Greene MI, Teng M, Liu J. Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21. J Biol Chem. 2011 Sep 9;286(36):31676-83. Epub 2011 Jun 16. PMID:21680730 doi:10.1074/jbc.M111.235184

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