3ri1: Difference between revisions
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[[Image:3ri1. | [[Image:3ri1.png|left|200px]] | ||
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[[Category: Palma, R.]] | [[Category: Palma, R.]] | ||
[[Category: Volckova, E.]] | [[Category: Volckova, E.]] | ||
[[Category: Fgfr1 kinase]] | |||
[[Category: Fgfr2 kinase]] | |||
[[Category: Inactive conformation]] | |||
[[Category: Kinase-inhibitor complex]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 07:33, 30 October 2011
Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069
Template:ABSTRACT PUBMED 21454610
About this Structure
3ri1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Eathiraj S, Palma R, Hirschi M, Volckova E, Nakuci E, Castro J, Chen CR, Chan TC, France DS, Ashwell MA. A novel mode of protein kinase inhibition exploiting hydrophobic motifs of auto-inhibited kinases: discovery of ATP independent inhibitors of fibroblast growth factor receptor (FGFR). J Biol Chem. 2011 Mar 24. PMID:21454610 doi:10.1074/jbc.M110.213736
