2wpf: Difference between revisions

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{{Seed}}
[[Image:2wpf.png|left|200px]]
[[Image:2wpf.jpg|left|200px]]


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===TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00085762)===
===TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00085762)===


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==About this Structure==
==About this Structure==
2WPF is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPF OCA].  
[[2wpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPF OCA].  
 
==Reference==
<ref group="xtra">PMID:021851087</ref><references group="xtra"/>
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanothione-disulfide reductase]]
[[Category: Trypanothione-disulfide reductase]]
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[[Category: Sleeping sickness]]
[[Category: Sleeping sickness]]
[[Category: Trypanosomiasis]]
[[Category: Trypanosomiasis]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:44:59 2010''

Revision as of 08:10, 30 October 2011

File:2wpf.png

Template:STRUCTURE 2wpf

TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00085762)

Template:ABSTRACT PUBMED 21851087

About this Structure

2wpf is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  1. Patterson S, Alphey MS, Jones DC, Shanks EJ, Street IP, Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography. J Med Chem. 2011 Oct 13;54(19):6514-30. Epub 2011 Sep 1. PMID:21851087 doi:10.1021/jm200312v

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