2wpf: Difference between revisions

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Revision as of 08:11, 30 October 2011

File:2wpf.png

Template:STRUCTURE 2wpf

TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00085762)

Template:ABSTRACT PUBMED 21851087

About this Structure

2wpf is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  1. Patterson S, Alphey MS, Jones DC, Shanks EJ, Street IP, Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography. J Med Chem. 2011 Oct 13;54(19):6514-30. Epub 2011 Sep 1. PMID:21851087 doi:10.1021/jm200312v

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OCA

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