Cluster of Differentiation CD38: Difference between revisions
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[[Image:3gc6a.jpg|left|200px|thumb|Crystal Structure of bovine Cluster of Differentiation 38 (CD38) [[3gc6]]]] | [[Image:3gc6a.jpg|left|200px|thumb|Crystal Structure of bovine Cluster of Differentiation 38 (CD38) [[3gc6]]]] | ||
{{STRUCTURE_3gc6| PDB=3gc6 | SIZE=300| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Cluster of Differentiation 38 (CD38) [[3gc6]] }} | {{STRUCTURE_3gc6| PDB=3gc6 | SIZE=300| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }} | ||
[[Cluster of Differentiation 38]] (CD38), known also as [[ADP-ribosyl cyclase 1]] (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. The images at the left and at the right correspond to one representative CD38, ''i.e.'' the crystal structure of bovine Cluster of Differentiation 38 ([[3gc6]]). | [[Cluster of Differentiation 38]] (CD38), known also as [[ADP-ribosyl cyclase 1]] (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. The images at the left and at the right correspond to one representative CD38, ''i.e.'' the crystal structure of bovine Cluster of Differentiation 38 ([[3gc6]]). | ||
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== 3D Structures of Cluster of Differentiation 38 == | == 3D Structures of Cluster of Differentiation 38 == | ||
''Update November 2011'' | |||
=== CD38 === | === CD38 === | ||
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[[2i67]] - hCD38 (mutant)+ADPR<br /> | [[2i67]] - hCD38 (mutant)+ADPR<br /> | ||
[[2hct]] - hCD38 enzymatic domain (mutant)+NMN<br /> | [[2hct]] - hCD38 enzymatic domain (mutant)+NMN<br /> | ||
[[3ofs]] - hCD38 enzymatic domain (mutant)+ ARA-2 F-ADPR<br /> | |||
[[3raj]] - hCD38 enzymatic domain (mutant)+ FAB | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
