Sandbox 38: Difference between revisions
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[[Image:http://www.grin.com/object/external_document.277519/39fb03ee7469e8a03df51acd066b17b2_LARGE.png]] | [[Image:http://www.grin.com/object/external_document.277519/39fb03ee7469e8a03df51acd066b17b2_LARGE.png]] | ||
== '''History''' == | == '''History:''' == | ||
Papain was originally discovered during the colonial period in Congo. The native inhabitants discovered that wrapping their elephant meat in papaya leaves helped to tenderize the meat. While they did not know the direct cause, this was when the proteolytic enzyme was first discovered. The active binding site of this enzyme was first discovered by Drenth et al., through the crystallographic analysis of the enzymes structure. | Papain was originally discovered during the colonial period in Congo. The native inhabitants discovered that wrapping their elephant meat in papaya leaves helped to tenderize the meat. While they did not know the direct cause, this was when the proteolytic enzyme was first discovered. The active binding site of this enzyme was first discovered by Drenth et al., through the crystallographic analysis of the enzymes structure. | ||
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== Hydrophobicity and Hydrophilicity == | == '''Hydrophobicity and Hydrophilicity''' == | ||
These charged residues contribute to the overall hydrophobicity and hydrophilicity of the enzyme, as the <scene name='Sandbox_38/Hydrophobic_and_polar_residues/2'>hydrophobic and hydrophilic regions</scene> are also able to be viewed. The polar amino acids have a purple color and the hydrophobic residues are gray. <scene name='Sandbox_38/Papain_ligand_binding/1'>ligands of Papain</scene> | These charged residues contribute to the overall hydrophobicity and hydrophilicity of the enzyme, as the <scene name='Sandbox_38/Hydrophobic_and_polar_residues/2'>hydrophobic and hydrophilic regions</scene> are also able to be viewed. The polar amino acids have a purple color and the hydrophobic residues are gray. <scene name='Sandbox_38/Papain_ligand_binding/1'>ligands of Papain</scene> | ||
<scene name='Sandbox_38/Hydrophobic_residues/1'>Hydrophobic Residues</scene>. | <scene name='Sandbox_38/Hydrophobic_residues/1'>Hydrophobic Residues</scene>. | ||
</StructureSection> | </StructureSection> | ||
