3nyp: Difference between revisions

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==Reference==
==Reference==
<ref group="xtra">PMID:21221451</ref><references group="xtra"/>
<ref group="xtra">PMID:021221451</ref><references group="xtra"/>
[[Category: Campbell, N H.]]
[[Category: Campbell, N H.]]
[[Category: Neidle, S.]]
[[Category: Neidle, S.]]
[[Category: Acridine]]
[[Category: Anti-parallel]]
[[Category: Bimolecular]]
[[Category: Bsu-6039]]
[[Category: Bsu6039]]
[[Category: Dna]]
[[Category: G-quadruplex]]
[[Category: Macromolecule]]
[[Category: Oxtyricha nova]]
[[Category: Quadruplex]]
[[Category: Telomere]]

Revision as of 09:56, 16 November 2011

File:3nyp.png

Template:STRUCTURE 3nyp

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains

Template:ABSTRACT PUBMED 21221451

About this Structure

3nyp is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Campbell NH, Smith DL, Reszka AP, Neidle S, O'Hagan D. Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA. Org Biomol Chem. 2011 Mar 7;9(5):1328-31. Epub 2011 Jan 10. PMID:21221451 doi:10.1039/c0ob00886a

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