2ovr: Difference between revisions

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Revision as of 11:14, 16 November 2011

File:2ovr.png

Template:STRUCTURE 2ovr

Structure of the Skp1-Fbw7-CyclinEdegN complex

Template:ABSTRACT PUBMED 17434132

About this Structure

2ovr is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Hao B, Oehlmann S, Sowa ME, Harper JW, Pavletich NP. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol Cell. 2007 Apr 13;26(1):131-43. PMID:17434132 doi:https://dx.doi.org/10.1016/j.molcel.2007.02.022
  2. Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat Biotechnol. 2010 Jul;28(7):733-7. Epub 2010 Jun 27. PMID:20581844 doi:10.1038/nbt.1646

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