2hap: Difference between revisions

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{{Seed}}
[[Image:2hap.png|left|200px]]
[[Image:2hap.png|left|200px]]


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==About this Structure==
==About this Structure==
2HAP is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAP OCA].  
[[2hap]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAP OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:9886287</ref><references group="xtra"/>
<ref group="xtra">PMID:009886287</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Guarente, L.]]
[[Category: Guarente, L.]]
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[[Category: Zhang, L.]]
[[Category: Zhang, L.]]
[[Category: Asymmetry]]
[[Category: Asymmetry]]
[[Category: Complex transcription factor/dna]]
[[Category: Complex transcription factor-dna]]
[[Category: Gene regulation-dna complex]]
[[Category: Hyperactive mutant]]
[[Category: Hyperactive mutant]]
[[Category: Transcriptional activation]]
[[Category: Transcriptional activation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:36:58 2009''

Revision as of 11:18, 16 November 2011

File:2hap.png

Template:STRUCTURE 2hap

STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION

Template:ABSTRACT PUBMED 9886287

About this Structure

2hap is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. King DA, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nat Struct Biol. 1999 Jan;6(1):22-7. PMID:9886287 doi:10.1038/4893
  2. Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630

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