Amyloid beta: Difference between revisions

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 Tau proteins function to stabilize microtubules [[http://en.wikipedia.org/wiki/Tau_protein]]. Association between Tau proteins and amyloid beta results in dissociation of tau from microtubules which collapses the axonal structure leading to the death of neurons.<ref name="alz" />
-'''Binding ApoE, ABAD, and catalase'''
+'''Binding ApoE'''
-By binding these proteins amyloid beta alters the normal activities and leads to over production of amyloid beta and oxidative stress.
+Apolipoprotein E is normally involved in lipoprotein metabolism and transfer but it has been shown to play a role in the development of Alzheimers. ApoE4 has the most affinity for amyloid beta and uses the low-density lipoprotein-related protein receptor to internalize amyloid beta into neurons it also promotes the production od amyloid beta by stimulating APP recycling. It is also theorized that apolipoproteins promote the aggregation of amyloid beta into toxic oligomers.<ref name="alz" />
+'''Binding ABAD'''
+'''Binding Catalase'''
 ==Prevention==

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