Cowpea Chlorotic Mottle Virus: Difference between revisions
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<scene name='Cowpea_Chlorotic_Mottle_Virus/Full_capsid/2'>Assembled Capsid</scene> | <scene name='Cowpea_Chlorotic_Mottle_Virus/Full_capsid/2'>Assembled Capsid</scene> | ||
The viral capsid of CCMV is a complex of proteins stabilized by metal coordination between capsomeres and RNA binding on its internal surface. The viral genome encodes three capsid proteins that are chemically identical. These subunits, arbitrarily called A, B, and C, dimerize with each other and assemble into into hexamers and pentamers that comprise the viral capsomeres.<ref name=Speir>PMID:7743132</ref> The complete capsid structure takes the form of a truncated icosahedron (20 faces). It is described as a T=3 capsid, where the T value describes the number of structural units per equilateral face of the icosahedron. | The viral capsid of CCMV is a complex of proteins stabilized by metal coordination between capsomeres and RNA binding on its internal surface. The viral genome encodes three capsid proteins that are chemically identical. These subunits, arbitrarily called A, B, and C, dimerize with each other and assemble into into hexamers and pentamers that comprise the viral capsomeres.<ref name=Speir>PMID:7743132</ref> The complete capsid structure takes the form of a truncated icosahedron (20 faces). It is described as a T=3 capsid, where the T value describes the number of structural units per equilateral face of the icosahedron. <ref name=http://www.nlv.ch/Virologytutorials/Structure.htm</ref> | ||
'''Capsomere Structure''' | '''Capsomere Structure''' | ||
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<ref name=Speir>PMID:7743132</ref> | <ref name=Speir>PMID:7743132</ref> | ||
{{Reflist}} | {{Reflist}} | ||
Revision as of 04:15, 30 November 2011
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Self-Assembling Cowpea Chlorotic Mottle Virus Capsid: Nanoreactor and Scaffold for Molecular Synthesis
Introduction
Protein Core with Stabilizing RNA Interactions
General Capsid Structure
The viral capsid of CCMV is a complex of proteins stabilized by metal coordination between capsomeres and RNA binding on its internal surface. The viral genome encodes three capsid proteins that are chemically identical. These subunits, arbitrarily called A, B, and C, dimerize with each other and assemble into into hexamers and pentamers that comprise the viral capsomeres.[1] The complete capsid structure takes the form of a truncated icosahedron (20 faces). It is described as a T=3 capsid, where the T value describes the number of structural units per equilateral face of the icosahedron. Cite error: Closing </ref> missing for <ref> tag
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Michal Harel, Alexander Berchansky, Joel L. Sussman, Inna Blyakhman
