Group:MUZIC:DARP: Difference between revisions
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Diabetes related ankyrin repeat protein DARP (Ankrd23) and its two close homologs Ankrd2/Arpp and Ankrd1/CARP correspond to a conserved gene family of muscle ankyrin repeat proteins (MARPs). <ref name='one'>PMID 14583192</ref> DARP is expressed in both heart and skeletal muscle (in addition to brown fat) and was identified by its upregulation in Type 2 diabetes and insulin-resistant animals, suggesting a potential role in energy metabolism. <ref name='two'>PMID 12456686 </ref> | Diabetes related ankyrin repeat protein DARP (Ankrd23) and its two close homologs Ankrd2/Arpp and Ankrd1/CARP correspond to a conserved gene family of muscle ankyrin repeat proteins (MARPs). <ref name='one'>PMID 14583192</ref> DARP is expressed in both heart and skeletal muscle (in addition to brown fat) and was identified by its upregulation in Type 2 diabetes and insulin-resistant animals, suggesting a potential role in energy metabolism. <ref name='two'>PMID 12456686 </ref> | ||
{{ | {{STRUCTURE_1N0Q | PDB=1N0Q}} | ||
== Structure == | == Structure == | ||
