Sandbox 212: Difference between revisions
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The carnitine acetyltransferases (also known as CATs) belong to the family of enzymes known as the carnitine acyltransferases, which also includes carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). | The carnitine acetyltransferases (also known as CATs) belong to the family of enzymes known as the carnitine acyltransferases, which also includes carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). | ||
The three known classes of carnitine acyltransferases differ in their acyl group specificity. Carnitine acetyltransferase has a substrate preference for short chain acyl-CoAs whereas carnitine palmityltransferases and carnitine palmityltransferases show preference for long chain acyl-CoAs.They are found in the mitochondrial matrix. Carnitine acetyltransferases are localized in both the outer membrane and the inner membrane. | The three known classes of carnitine acyltransferases differ in their acyl group specificity. Carnitine acetyltransferase has a substrate preference for short chain acyl-CoAs whereas carnitine palmityltransferases and carnitine palmityltransferases show preference for long chain acyl-CoAs.They are found in the mitochondrial matrix. Carnitine acetyltransferases are localized in both the outer membrane and the inner membrane. | ||
<Structure load='1ndf' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | |||
= Carnitine acetyltransferase = | |||
== Structure of Carnitine acetyltransferase == | == Structure of Carnitine acetyltransferase == | ||
=== Overall structure === | |||
=== THE ACTIVE SITE TUNNEL === | |||
=== THE CARNITINE BINDING SITE === | |||
=== THE CoA BINDING SITE === | |||
=== THE FATTY ACID BINDING SITE === | |||
== Biological function == | == Biological function == | ||
