Sandbox 300: Difference between revisions
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The 3D structure is build up of three α-helixes and it consists of five extracellular domains, which are designated as E, D, A, B and C. Furthermore the protein contains cell-wall spanning regions, called X<sub>r</sub> and X<sub>c</sub>, and a hydrophobic membrane spanning domain, which is distal to LPXTG and consists of 18-20 residues<ref>Hartleib, J., Köhler, N., Dickinson, R. B., Chhatwal, G. S., Sixma, J. J., M, O., Foster, T. J., et al. (2000). Protein A is the von Willebrand factor binding protein on Staphylococcus aureus, 2149-2156</ref>. Protein A exists in a secreted and a cell wall anchored form. If it is bound to the cell wall of ''Staphylococcus aureus'' it is covalently linked to the peptidoglycan via its C-terminal domain. | The 3D structure is build up of three α-helixes and it consists of five extracellular domains, which are designated as E, D, A, B and C. Furthermore the protein contains cell-wall spanning regions, called X<sub>r</sub> and X<sub>c</sub>, and a hydrophobic membrane spanning domain, which is distal to LPXTG and consists of 18-20 residues<ref>Hartleib, J., Köhler, N., Dickinson, R. B., Chhatwal, G. S., Sixma, J. J., M, O., Foster, T. J., et al. (2000). Protein A is the von Willebrand factor binding protein on Staphylococcus aureus, 2149-2156</ref>. Protein A exists in a secreted and a cell wall anchored form. If it is bound to the cell wall of ''Staphylococcus aureus'' it is covalently linked to the peptidoglycan via its C-terminal domain. | ||
[[Image:Spa-1.jpg]] | |||
==Function associated to this protein== | ==Function associated to this protein== | ||
