Sandbox 212: Difference between revisions
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There are only slight conformational changes in the enzyme upon carnitine binding.“The only significant conformational difference in the active site between the free enzyme and the carnitine complex is in the side chain of <font color='#90E050'>'''serine454'''</font>, which adopts a different rotamer to have better hydrogen-bonding interactions with the carboxylate of carnitine.” (Cry. Structure) | There are only slight conformational changes in the enzyme upon carnitine binding.“The only significant conformational difference in the active site between the free enzyme and the carnitine complex is in the side chain of <font color='#90E050'>'''serine454'''</font>, which adopts a different rotamer to have better hydrogen-bonding interactions with the carboxylate of carnitine.” (Cry. Structure) | ||
</StructureSection> | </StructureSection> | ||
== | == The Catalytic Mechanism of Carnitine Acyltransferases== | ||
[[Image:Machanism fatty acid transfer.jpg|thumb|400px]] | [[Image:Machanism fatty acid transfer.jpg|thumb|400px]] | ||
