3csi: Difference between revisions

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Revision as of 05:48, 28 December 2011

File:3csi.png

Template:STRUCTURE 3csi

Crystal Structure of the Glutathione Transferase Pi allelic variant*C, I104V/A113V, in complex with the Chlorambucil-Glutathione Conjugate

Template:ABSTRACT PUBMED 18511072

About this Structure

3csi is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Parker LJ, Ciccone S, Italiano LC, Primavera A, Oakley AJ, Morton CJ, Hancock NC, Bello ML, Parker MW. The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J Mol Biol. 2008 Jun 27;380(1):131-44. Epub 2008 May 4. PMID:18511072 doi:10.1016/j.jmb.2008.04.066

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